Pathways to prevention

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Two pathways to prevention.

Health promotion and disease prevention programs are becoming important components of contemporary health care. There are at least 2 pathways to the enhancement of population health status through disease prevention. The first pathway requires the early diagnosis and treatment of disease. The second pathway promotes healthy lifestyles and disregards the requirement that a condition must be diag...

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New Pathways to Disease Prevention

VOLUME 115 | NUMBER 2 | February 2007 • Environmental Health Perspectives As scientists, communication—not only with those outside our area of expertise but also with those within our scientific sphere—is an important responsibility, though often an ongoing challenge. As NIEHS director, I increasingly realize that, as the writer André Gide said, “The most important things to say are those which...

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Causal pathways and prevention.

It is 110 years since Sir William Osler published his little book on the cerebral palsies of childhood1. Less than 10 years later Freud published his observations2. And if we are looking for landmarks, perhaps the next is Crothers and Paine’s book, published 40 years ago3. Ingram’s ‘Paediatric Aspects of Cerebral Palsy’ follows this, published in 19744. But Little’s paper predates all of these5...

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Apoptosis: from Signalling Pathways to Therapeutic Tools

Apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. It is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal DNA fragmentation. Although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...

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Pathways and prevention in tobacco use.

Researchers have identified many risk factors for adolescent smoking initiation [1]. With the exception of tobacco-specific factors, these risk factors tend to be those characteristic of youth problematic behaviors in general [2]. This work is extremely valuable in identifying individual, family and school characteristics that either identify those youths at high risk of becoming smokers and/or...

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ژورنال

عنوان ژورنال: Science

سال: 2019

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.365.6455.745